Factory Price Colircusi Gentamicin - Enrofloxacin injection – Xinanran
Factory Price Colircusi Gentamicin - Enrofloxacin injection – Xinanran Detail:
Main ingredient
Characteristics
This product is colorless to pale yellow clear liquid.
Pharmacological action
Pharmacodynamic Enrofloxacin is a broad-spectrum bactericidal drug specially used for fluoroquinolone animals. For e. coli, salmonella, klebsiella, brucella, pasteurella, pleuropneumonia actinobacillus, erysipelas, bacillus proteus, clayey Mr Charest’s bacteria, suppurative corynebacterium, defeated blood pott’s bacteria, staphylococcus aureus, mycoplasma, chlamydia, etc all have good effect, on the role of pseudomonas aeruginosa and streptococcus is weak, weak effect on anaerobic bacteria. It has obvious post-antibacterial effect on sensitive bacteria. The antibacterial action mechanism of this product is to inhibit bacterial DNA rotase, interfere with the replication, transcription and repair of bacterial DNA recombination, bacterial can not grow and reproduce normally and die.
Pharmacokinetics The drug was absorbed quickly and completely by intramuscular injection. The bioavailability was 91.9% in pigs and 82% in cows. It is widely distributed in animals and can enter tissues and body fluids well. Except cerebrospinal fluid, the concentration of drugs in almost all tissues is higher than that in plasma. The main hepatic metabolism is the removal of the ethyl of the 7-piperazine ring to produce ciprofloxacin, followed by oxidation and glucuronic acid binding. Mainly through the kidney (renal tubular secretion and glomerular filtration) discharge, 15% ~ 50% in the original form from the urine. The elimination half-life of intramuscular injection was 5.9 hours in dairy cows, 1.5 ~ 4.5 hours in sheep, and 4.6 hours in pigs.
Drug Interactions
(1) This product has synergistic effect when combined with aminoglycosides or broad-spectrum penicillin.
(2) Ca2+, Mg2+, Fe3+, Al3+ and other heavy metal ions can chelate with this product, affecting the absorption.
(3) When combined with theophylline and caffeine, the plasma protein binding rate is reduced, and the concentration of theophylline and caffeine in blood is abnormally increased.
Even appear theophylline poisoning symptoms.
(4) This product has the effect of inhibiting liver drug enzymes, which can reduce the clearance rate of drugs mainly metabolized in the liver, and increase the blood concentration of drugs.
[Role and use] Quinolones antibacterial drugs. It is used for bacterial diseases and mycoplasma infections of livestock and poultry.
Adverse reactions
(1) Cartilage degeneration occurs in young animals, affecting bone development and causing claudication and pain.
(2) The reactions of digestive system include vomiting, loss of appetite, diarrhea, etc.
(3) Skin reactions include erythema, pruritus, urticaria and photosensitive reaction.
(4) Allergic reactions, ataxia and seizures are occasionally seen in dogs and cats.
Precautions
(1) It has potential excitatory effect on the central system and can induce epileptic seizures. It should be used with caution in dogs with epilepsy.
(2) Carnivores and animals with poor renal function use with caution, can occasionally crystallize urine.
(3) This product is not suitable for dogs before 8 weeks of age.
(4) The drug-resistant strains of this product are increasing, so it should not be used in the subtherapeutic dose for a long time.
Hebei Xinanran Biology Science And Technology Co., Ltd.
Address: No. 06, East Row 1, Konggang Street, Xinle Economic Development Zone, Hebei Province
Tel: 0311-85695628/85695638
Postcode: 050700
Product detail pictures:
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From the past few years, our firm absorbed and digested sophisticated technologies equally at home and abroad. Meanwhile, our organization staffs a group of experts devoted into the growth of Factory Price Colircusi Gentamicin - Enrofloxacin injection – Xinanran , The product will supply to all over the world, such as: Birmingham, United Kingdom, Casablanca, Since its foundation , the company keeps living up to the belief of "honest selling , best quality , people-orientation and benefits to customers. " We are doing everything to offer our customers with best services and best products . We promise that we'll be responsible all the way to the end once our services begin.
By Christopher Mabey from Jordan - 2017.01.11 17:15
The factory can meet continuously developing economic and market needs, so that their products are widely recognized and trusted, and that's why we chose this company.
By David from Honduras - 2018.12.05 13:53
