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Big discounting Enrofloxacin Humans - Enrofloxacin injection – Xinanran

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Big discounting Enrofloxacin Humans - Enrofloxacin injection – Xinanran Detail:

Main ingredient

Enrofloxacin

Characteristics

This product is colorless to pale yellow clear liquid.

Pharmacological action

Pharmacodynamic Enrofloxacin is a broad-spectrum bactericidal drug specially used for fluoroquinolone animals. For e. coli, salmonella, klebsiella, brucella, pasteurella, pleuropneumonia actinobacillus, erysipelas, bacillus proteus, clayey Mr Charest’s bacteria, suppurative corynebacterium, defeated blood pott’s bacteria, staphylococcus aureus, mycoplasma, chlamydia, etc all have good effect, on the role of pseudomonas aeruginosa and streptococcus is weak, weak effect on anaerobic bacteria. It has obvious post-antibacterial effect on sensitive bacteria. The antibacterial action mechanism of this product is to inhibit bacterial DNA rotase, interfere with the replication, transcription and repair of bacterial DNA recombination, bacterial can not grow and reproduce normally and die.

Pharmacokinetics The drug was absorbed quickly and completely by intramuscular injection. The bioavailability was 91.9% in pigs and 82% in cows. It is widely distributed in animals and can enter tissues and body fluids well. Except cerebrospinal fluid, the concentration of drugs in almost all tissues is higher than that in plasma. The main hepatic metabolism is the removal of the ethyl of the 7-piperazine ring to produce ciprofloxacin, followed by oxidation and glucuronic acid binding. Mainly through the kidney (renal tubular secretion and glomerular filtration) discharge, 15% ~ 50% in the original form from the urine. The elimination half-life of intramuscular injection was 5.9 hours in dairy cows, 1.5 ~ 4.5 hours in sheep, and 4.6 hours in pigs.

Drug Interactions

(1) This product has synergistic effect when combined with aminoglycosides or broad-spectrum penicillin.

(2) Ca2+, Mg2+, Fe3+, Al3+ and other heavy metal ions can chelate with this product, affecting the absorption.

(3) When combined with theophylline and caffeine, the plasma protein binding rate is reduced, and the concentration of theophylline and caffeine in blood is abnormally increased.

Even appear theophylline poisoning symptoms.

(4) This product has the effect of inhibiting liver drug enzymes, which can reduce the clearance rate of drugs mainly metabolized in the liver, and increase the blood concentration of drugs.

[Role and use] Quinolones antibacterial drugs. It is used for bacterial diseases and mycoplasma infections of livestock and poultry.

Adverse reactions

(1) Cartilage degeneration occurs in young animals, affecting bone development and causing claudication and pain.

(2) The reactions of digestive system include vomiting, loss of appetite, diarrhea, etc.

(3) Skin reactions include erythema, pruritus, urticaria and photosensitive reaction.

(4) Allergic reactions, ataxia and seizures are occasionally seen in dogs and cats.

Precautions

(1) It has potential excitatory effect on the central system and can induce epileptic seizures. It should be used with caution in dogs with epilepsy.

(2) Carnivores and animals with poor renal function use with caution, can occasionally crystallize urine.

(3) This product is not suitable for dogs before 8 weeks of age.

(4) The drug-resistant strains of this product are increasing, so it should not be used in the subtherapeutic dose for a long time.

Hebei Xinanran Biology Science And Technology Co., Ltd.

Address: No. 06, East Row 1, Konggang Street, Xinle Economic Development Zone, Hebei Province

Tel: 0311-85695628/85695638

Postcode: 050700


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Big discounting Enrofloxacin Humans - Enrofloxacin injection – Xinanran detail pictures

Big discounting Enrofloxacin Humans - Enrofloxacin injection – Xinanran detail pictures


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We support our purchasers with ideal high-quality merchandise and significant level company. Becoming the specialist manufacturer in this sector, we now have received loaded practical encounter in producing and managing for Big discounting Enrofloxacin Humans - Enrofloxacin injection – Xinanran , The product will supply to all over the world, such as: Dubai, Amman, European, We focus on providing service for our clients as a key element in strengthening our long-term relationships. Our continual availability of high grade products in combination with our excellent pre-sale and after-sales service ensures strong competitiveness in an increasingly globalized market. We are willing to cooperate with business friends from at home and abroad and create a great future together.
  • Product variety is complete, good quality and inexpensive, the delivery is fast and transport is security, very good, we are happy to cooperate with a reputable company!
    5 Stars By Iris from Norway - 2017.08.28 16:02
    Speaking of this cooperation with the Chinese manufacturer, I just want to say"well dodne", we are very satisfied.
    5 Stars By Diana from Malaysia - 2017.08.15 12:36
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